The human brain is probably the 'final frontier'...
Blogger Jason Goldman reviews some of what we know/believe about mathematical dysfunction of the brain here, based in part on case-studies of patients with different brain lesions and on fMRI studies:
http://tinyurl.com/2dz2m3a
This was actually the 4th in a series of related posts Jason did that can be looked up here:
http://tinyurl.com/266o57k
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