People's genetics and metabolism differ... this is such an obvious truism that it's kind of a shame articles like this even need to be written... but folks prefer thinking along binary, all-or-nothing, black-and-white lines, instead of in terms of continuities and nuances, so yes it needs be said aloud:
https://theconversation.com/why-prescription-drugs-can-work-differently-for-different-people-168645
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